Suberoylanilide Hydroxamic Acid Attenuates Autoimmune Arthritis by Suppressing Th17 Cells through NR1D1 Inhibition

Suberoylanilide Hydroxamic Acid Attenuates Autoimmune Arthritis by Suppressing Th17 Cells through NR1D1 Inhibition

Rheumatoid arthritis (RA) is a type of systemic autoimmune arthritis that causes joint inflammation and destruction. One of the pathological mechanisms of RA is known to involve histone acetylation. Although the histone deacetylase (HDAC) inhibitor suberoylanilide hydroxamic acid (SAHA) can attenuat...

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Bibliographic Details
Main Authors: Da Som Kim, Hong-Ki Min, Eun Kyung Kim, Seung Cheon Yang, Hyun Sik Na, Seon-Yeong Lee, Jeong-Won Choi, Kyung-Ah Jung, Seung-Ki Kwok, Sung-Hwan Park, Mi-La Cho
Format: Article
Language:English
Published: Hindawi Limited 2019-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/2019/5648987

Internet

http://dx.doi.org/10.1155/2019/5648987

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