RNA polymerase II clusters form in line with surface condensation on regulatory chromatin

RNA polymerase II clusters form in line with surface condensation on regulatory chromatin

Abstract It is essential for cells to control which genes are transcribed into RNA. In eukaryotes, two major control points are recruitment of RNA polymerase II (Pol II) into a paused state, and subsequent pause release toward transcription. Pol II recruitment and pause release occur in association...

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Bibliographic Details
Main Authors: Agnieszka Pancholi, Tim Klingberg, Weichun Zhang, Roshan Prizak, Irina Mamontova, Amra Noa, Marcel Sobucki, Andrei Yu Kobitski, Gerd Ulrich Nienhaus, Vasily Zaburdaev, Lennart Hilbert
Format: Article
Language:English
Published: Wiley 2021-09-01
Series:Molecular Systems Biology
Subjects:
active matter
gene regulation
nuclear organization
super‐resolution microscopy
transcriptional condensates
Online Access:https://doi.org/10.15252/msb.202110272

Internet

https://doi.org/10.15252/msb.202110272

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