HMGB1 in inflammation and cancer

Abstract High mobility group box 1 (HMGB1) is a non-histone chromatin-associated protein widely distributed in eukaryotic cells and is involved in DNA damage repair and genomic stability maintenance. In response to stimulus like bacteria or chemoradiotherapy, HMGB1 can translocate to extracellular c...

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Bibliographic Details
Main Authors: Shumin Wang, Yi Zhang
Format: Article
Language:English
Published: BMC 2020-08-01
Series:Journal of Hematology & Oncology
Subjects:
TLR
Online Access:http://link.springer.com/article/10.1186/s13045-020-00950-x