Laboratory Investigation of Hybrid IgG4 k/λ in MuSK Positive Myasthenia Gravis

Laboratory Investigation of Hybrid IgG4 k/λ in MuSK Positive Myasthenia Gravis

Myasthenia gravis with antibodies (Abs) against the muscle-specific tyrosine kinase (MuSK) is a rare autoimmune disorder (AD) of the neuromuscular junction (NMJ) and represents a prototype of AD with proven IgG4-mediated pathogenicity. Thanks to the mechanism of Fab-arm exchange (FAE) occurring in v...

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Bibliographic Details
Main Authors: Umberto Basile, Cecilia Napodano, Francesca Gulli, Krizia Pocino, Riccardo Di Santo, Laura Todi, Valerio Basile, Carlo Provenzano, Gabriele Ciasca, Mariapaola Marino
Format: Article
Language:English
Published: MDPI AG 2021-08-01
Series:International Journal of Molecular Sciences
Subjects:
biomarker
antibodies
personalized medicine
IgG4
Fab-arm exchange
hybrid k/λ
Online Access:https://www.mdpi.com/1422-0067/22/17/9142

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https://www.mdpi.com/1422-0067/22/17/9142

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