ARID5B, IKZF1 and non-genetic factors in the etiology of childhood acute lymphoblastic leukemia: the ESCALE study.

ARID5B, IKZF1 and non-genetic factors in the etiology of childhood acute lymphoblastic leukemia: the ESCALE study.

Genome-wide association studies (GWAS) have identified that frequent polymorphisms in ARID5B and IKZF1, two genes involved in lymphoid differentiation, increase the risk of childhood acute lymphoblastic leukemia (ALL). These findings markedly modified the current field of research on the etiology of...

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Main Authors: Jérémie Rudant, Laurent Orsi, Audrey Bonaventure, Stéphanie Goujon-Bellec, André Baruchel, Arnaud Petit, Yves Bertrand, Brigitte Nelken, Marlène Pasquet, Gérard Michel, Laure Saumet, Pascal Chastagner, Stéphane Ducassou, Yves Réguerre, Denis Hémon, Jacqueline Clavel
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0121348

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https://doi.org/10.1371/journal.pone.0121348

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