β-Catenin is required for the tumorigenic behavior of triple-negative breast cancer cells.

Our previous data illustrated that activation of the canonical Wnt signaling pathway was enriched in triple-negative breast cancer and associated with reduced overall survival in all patients. To determine whether Wnt signaling may be a promising therapeutic target for triple-negative breast cancer,...

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Bibliographic Details
Main Authors: Jinhua Xu, Jenifer R Prosperi, Noura Choudhury, Olufunmilayo I Olopade, Kathleen H Goss
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4319896?pdf=render