Microbiota-dependent metabolite and cardiovascular disease marker trimethylamine-N-oxide (TMAO) is associated with monocyte activation but not platelet function in untreated HIV infection

Abstract Background HIV infection is associated with increased risk of cardiovascular disease beyond that explained by traditional risk factors. Altered gut microbiota, microbial translocation, and immune activation have been proposed as potential triggers. The microbiota-dependent metabolite trimet...

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Bibliographic Details
Main Authors: Judith M. Haissman, Anna K. Haugaard, Sisse R. Ostrowski, Rolf K. Berge, Johannes R. Hov, Marius Trøseid, Susanne D. Nielsen
Format: Article
Language:English
Published: BMC 2017-06-01
Series:BMC Infectious Diseases
Online Access:http://link.springer.com/article/10.1186/s12879-017-2547-x