Administration of orexin receptor 1 antagonist into the rostral ventromedial medulla increased swim stress-induced antinociception in rat

Objective(s): Intracerebroventricular injection of orexin-A (hypocretin-1) antagonist has been shown to inhibit stress-induced analgesia. However the locations of central sites that may mediate these effects have not been totally demonstrated. This study was performed to investigate the role of rost...

Full description

Bibliographic Details
Main Authors: Neda Soliemani, Alireza Moslem, Ali Shamsizadeh, Hassan Azhdari-Zarmehri
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2016-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/article_6939_eb009b0070dabf2abd8e16a763467d05.pdf