PrPSc formation and clearance as determinants of prion tropism.

PrPSc formation and clearance as determinants of prion tropism.

Prion strains are characterized by strain-specific differences in neuropathology but can also differ in incubation period, clinical disease, host-range and tissue tropism. The hyper (HY) and drowsy (DY) strains of hamster-adapted transmissible mink encephalopathy (TME) differ in tissue tropism and s...

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Bibliographic Details
Main Authors: Ronald A Shikiya, Katie A Langenfeld, Thomas E Eckland, Jonathan Trinh, Sara A M Holec, Candace K Mathiason, Anthony E Kincaid, Jason C Bartz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-03-01
Series:PLoS Pathogens
Online Access:http://europepmc.org/articles/PMC5386299?pdf=render

Internet

http://europepmc.org/articles/PMC5386299?pdf=render

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