Production, purification and characterization of recombinant human R-spondin1 (RSPO1) protein stably expressed in human HEK293 cells

Production, purification and characterization of recombinant human R-spondin1 (RSPO1) protein stably expressed in human HEK293 cells

Abstract Background The R-Spondin proteins comprise a family of secreted proteins, known for their important roles in cell proliferation, differentiation and death, by inducing the Wnt pathway. Several studies have demonstrated the importance of RSPOs in regulation of a number of tissue-specific pro...

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Bibliographic Details
Main Authors: Gabriel Levin, Bruna Andrade Aguiar Koga, Gustavo Gross Belchior, Ana Claudia Oliveira Carreira, Mari Cleide Sogayar
Format: Article
Language:English
Published: BMC 2020-01-01
Series:BMC Biotechnology
Subjects:
Tissue engineering
Heterologous mammalian protein expression system
Recombinant human R-spondin1 (RSPO1)
Peptide growth factors
HEK293 cells
Online Access:https://doi.org/10.1186/s12896-020-0600-0

Internet

https://doi.org/10.1186/s12896-020-0600-0

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