Multiomics landscape of synovial fibroblasts in rheumatoid arthritis

Abstract Background Rheumatoid arthritis (RA) is an autoimmune disease characterized by tumor-like hyperplasia and inflammation of the synovium, which causes synovial cell invasion into the bone and cartilage. In RA pathogenesis, various molecules in effector cells (i.e., immune cells and mesenchyma...

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Bibliographic Details
Main Authors: Haruka Tsuchiya, Mineto Ota, Keishi Fujio
Format: Article
Language:English
Published: BMC 2021-03-01
Series:Inflammation and Regeneration
Subjects:
Online Access:https://doi.org/10.1186/s41232-021-00157-8