Induction of HCA587-specific antitumor immunity with HCA587 protein formulated with CpG and ISCOM in mice.

HCA587 (also known as MAGE-C2) is a "cancer-testis" antigen highly expressed in a number of malignancies with unique immunological properties, making it a promising target for tumor immunotherapy. In this report, we demonstrated that HCA587 protein, when formulated with adjuvants CpG-conta...

Full description

Bibliographic Details
Main Authors: Juanjuan Chen, Lijie Zhang, Weigang Wen, Jiaqing Hao, Pumei Zeng, Xiaoping Qian, Yu Zhang, Yanhui Yin
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3469506?pdf=render