Intestinal Stem Cell Niche: The Extracellular Matrix and Cellular Components

The intestinal epithelium comprises a monolayer of polarised columnar cells organised along the crypt-villus axis. Intestinal stem cells reside at the base of crypts and are constantly nourished by their surrounding niche for maintenance, self-renewal, and differentiation. The cellular microenvironm...

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Bibliographic Details
Main Authors: Laween Meran, Anna Baulies, Vivian S. W. Li
Format: Article
Language:English
Published: Hindawi Limited 2017-01-01
Series:Stem Cells International
Online Access:http://dx.doi.org/10.1155/2017/7970385