Formation and optimization of three-dimensional organoids generated from urine-derived stem cells for renal function in vitro

Formation and optimization of three-dimensional organoids generated from urine-derived stem cells for renal function in vitro

Abstract Background Organoids play an important role in basic research, drug screening, and regenerative medicine. Here, we aimed to develop a novel kind of three-dimensional (3D) organoids generated from urine-derived stem cells (USCs) and to explore whether kidney-specific extracellular matrix (kE...

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Bibliographic Details
Main Authors: Guoliang Sun, Beichen Ding, Meimei Wan, Liang Chen, John Jackson, Anthony Atala
Format: Article
Language:English
Published: BMC 2020-07-01
Series:Stem Cell Research & Therapy
Subjects:
Urine-derived stem cells
Organoids
Extracellular matrix
Drug screening
Renal function
Online Access:http://link.springer.com/article/10.1186/s13287-020-01822-4

Internet

http://link.springer.com/article/10.1186/s13287-020-01822-4

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