Age-Related Modifications in Circulating IL-15 Levels in Humans

Aging is associated to a progressive establishing of a chronic inflammatory state linked to a continuous long exposure to antigens. Since IL-15 stimulates the proliferation of memory T cells and the immunosenescence is characterized by accumulation of memory T cells and exhaustion of naive T cells,...

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Bibliographic Details
Main Authors: Sebastiano Gangemi, Giorgio Basile, Daniela Monti, Rosaria Alba Merendino, Giuseppe Di Pasquale, Ursula Bisignano, Vittorio Nicita-Mauro, Claudio Franceschi
Format: Article
Language:English
Published: Hindawi Limited 2005-01-01
Series:Mediators of Inflammation
Online Access:http://dx.doi.org/10.1155/MI.2005.245