Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs.

Antibodies to S. aureus LukS-PV Attenuated Subunit Vaccine Neutralize a Broad Spectrum of Canonical and Non-Canonical Bicomponent Leukotoxin Pairs.

S. aureus vaccine development has proven particularly difficult. The conventional approach to achieve sterile immunity through opsonophagocytic killing has been largely unsuccessful. S. aureus is highly toxigenic and a great body of evidence suggests that a successful future vaccine for this organis...

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Bibliographic Details
Main Authors: Rajan P Adhikari, Thomas Kort, Sergey Shulenin, Tulasikumari Kanipakala, Nader Ganjbaksh, Mary-Claire Roghmann, Frederick W Holtsberg, M Javad Aman
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4569305?pdf=render

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http://europepmc.org/articles/PMC4569305?pdf=render

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