Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

Efflux Activity Differentially Modulates the Levels of Isoniazid and Rifampicin Resistance among Multidrug Resistant and Monoresistant Mycobacterium tuberculosis Strains

With the growing body of knowledge on the contribution of efflux activity to Mycobacterium tuberculosis drug resistance, increased attention has been given to the use of efflux inhibitors as adjuvants of tuberculosis therapy. Here, we investigated how efflux activity modulates the levels of efflux b...

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Bibliographic Details
Main Authors: Diana Machado, João Perdigão, Isabel Portugal, Marco Pieroni, Pedro A. Silva, Isabel Couto, Miguel Viveiros
Format: Article
Language:English
Published: MDPI AG 2018-03-01
Series:Antibiotics
Subjects:
efflux inhibitors
lineages
mutations
resistance levels
tuberculosis
verapamil
Online Access:http://www.mdpi.com/2079-6382/7/1/18

Internet

http://www.mdpi.com/2079-6382/7/1/18

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