Genotype-Based Gene Expression in Colon Tissue—Prediction Accuracy and Relationship with the Prognosis of Colorectal Cancer Patients

Genotype-Based Gene Expression in Colon Tissue—Prediction Accuracy and Relationship with the Prognosis of Colorectal Cancer Patients

Colorectal cancer (CRC) survival has environmental and inherited components. The expression of specific genes can be inferred based on individual genotypes—so called expression quantitative trait loci. In this study, we used the PrediXcan method to predict gene expression in normal colon tissue usin...

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Bibliographic Details
Main Authors: Heike Deutelmoser, Justo Lorenzo Bermejo, Axel Benner, Korbinian Weigl, Hanla A. Park, Mariam Haffa, Esther Herpel, Martin Schneider, Cornelia M. Ulrich, Michael Hoffmeister, Jenny Chang-Claude, Hermann Brenner, Dominique Scherer
Format: Article
Language:English
Published: MDPI AG 2020-10-01
Series:International Journal of Molecular Sciences
Subjects:
genotype-based gene expression
PrediXcan
colorectal cancer
survival
Online Access:https://www.mdpi.com/1422-0067/21/21/8150

Internet

https://www.mdpi.com/1422-0067/21/21/8150

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