Importance of subchondral bone in the pathogenesis and management of osteoarthritis from bench to bed

Osteoarthritis (OA) is the most common form of joint disorders, which is the leading cause of pain and walking disability in older adults. The primary concern of OA is loss of articular cartilage. Yet the integrity of articular cartilage relies on subchondral bone to provide mechanical support and n...

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Bibliographic Details
Main Authors: Chunyi Wen, Weijia William Lu, Kwong Yuen Chiu
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Journal of Orthopaedic Translation
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2214031X1300051X