Thyroxine transfer from cerebrospinal fluid into choroid plexus and brain is affected by brefeldin A, low sodium, BCH, and phloretin, in Ventriculo-Cisternal perfused rabbits

Thyroxine transfer from cerebrospinal fluid into choroid plexus and brain is affected by brefeldin A, low sodium, BCH, and phloretin, in Ventriculo-Cisternal perfused rabbits

Thyroxine (T4) hormone is synthesized by the thyroid gland and then released into the systemic circulation where it binds to a number of proteins. Dysfunction in T4 transport mechanisms has been demonstrated in multiple central nervous system (CNS) diseases including Alzheimer’s disease. In the pres...

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Bibliographic Details
Main Authors: Kazem eZibara, Ali eEl-Zein, Wissam eJoumaa, Stefania eMondello, Mohammad eEL-Sayyad, Nouhad eKassem
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-09-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Blood-Brain Barrier
transport
Brain Perfusion
Thyroid hormone
blood-CSF barrier
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00060/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fcell.2015.00060/full

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