Trained Immunity for Personalized Cancer Immunotherapy: Current Knowledge and Future Opportunities

Trained Immunity for Personalized Cancer Immunotherapy: Current Knowledge and Future Opportunities

Memory formation, guided by microbial ligands, has been reported for innate immune cells. Epigenetic imprinting plays an important role herein, involving histone modification after pathogen-/danger-associated molecular patterns (PAMPs/DAMPs) recognition by pattern recognition receptors (PRRs). Such...

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Bibliographic Details
Main Authors: Joana R. Lérias, Eric de Sousa, Georgia Paraschoudi, João Martins, Carolina Condeço, Nuno Figueiredo, Carlos Carvalho, Ernest Dodoo, Andreia Maia, Mireia Castillo-Martin, Antonio Beltrán, Dário Ligeiro, Martin Rao, Alimuddin Zumla, Markus Maeurer
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-01-01
Series:Frontiers in Microbiology
Subjects:
trained immunity
macrophages
dendritic cells
inflammation
cancer
pathogens
Online Access:https://www.frontiersin.org/article/10.3389/fmicb.2019.02924/full

Internet

https://www.frontiersin.org/article/10.3389/fmicb.2019.02924/full

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