Profiling Ribonucleotide and Deoxyribonucleotide Pools Perturbed by Remdesivir in Human Bronchial Epithelial Cells

Remdesivir (RDV) has generated much anticipation for its moderate effect in treating severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. However, the unsatisfactory survival rates of hospitalized patients limit its application to the treatment of coronavirus disease 2019 (COVID-1...

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Bibliographic Details
Main Authors: Yan Li, Hui-Xia Zhang, Wen-Di Luo, Christopher Wai Kei Lam, Cai-Yun Wang, Li-Ping Bai, Vincent Kam Wai Wong, Wei Zhang, Zhi-Hong Jiang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2021.647280/full