A peptidoglycan storm caused by β-lactam antibiotic’s action on host microbiota drives Candida albicans infection

A risk factor for invasive Candida albicans infection is the use of broad-spectrum antibiotics, but the reasons are poorly understood. Here, the authors show in mice that β-lactam antibiotics cause commensal bacteria to release peptidoglycan fragments that induce the invasive hyphal growth of C. alb...

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Bibliographic Details
Main Authors: Chew Teng Tan, Xiaoli Xu, Yuan Qiao, Yue Wang
Format: Article
Language:English
Published: Nature Publishing Group 2021-05-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-021-22845-2