A Monovalent and Trivalent MVA-Based Vaccine Completely Protects Mice Against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenge

A Monovalent and Trivalent MVA-Based Vaccine Completely Protects Mice Against Lethal Venezuelan, Western, and Eastern Equine Encephalitis Virus Aerosol Challenge

Venezuelan, eastern and western equine encephalitis viruses (EEV) can cause severe disease of the central nervous system in humans, potentially leading to permanent damage or death. Yet, no licensed vaccine for human use is available to protect against these mosquito-borne pathogens, which can be ae...

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Bibliographic Details
Main Authors: Lisa Henning, Kathrin Endt, Robin Steigerwald, Michael Anderson, Ariane Volkmann
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
modified vaccinia Ankara (MVA)
vaccines
efficacy
alphavirus
equine encephalitis
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.598847/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.598847/full

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