Translating preventive chemotherapy prevalence thresholds for Schistosoma mansoni from the Kato-Katz technique into the point-of-care circulating cathodic antigen diagnostic test.

BACKGROUND:Intervention guidelines against Schistosoma mansoni are based on the Kato-Katz technique. However, Kato-Katz thick smears show low sensitivity, especially for light-intensity infections. The point-of-care circulating cathodic antigen (POC-CCA) is a promising rapid diagnostic test detectin...

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Bibliographic Details
Main Authors: Oliver Bärenbold, Amadou Garba, Daniel G Colley, Fiona M Fleming, Ayat A Haggag, Reda M R Ramzy, Rufin K Assaré, Edridah M Tukahebwa, Jean B Mbonigaba, Victor Bucumi, Biruck Kebede, Makoy S Yibi, Aboulaye Meité, Jean T Coulibaly, Eliézer K N'Goran, Louis-Albert Tchuem Tchuenté, Pauline Mwinzi, Jürg Utzinger, Penelope Vounatsou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-12-01
Series:PLoS Neglected Tropical Diseases
Online Access:https://doi.org/10.1371/journal.pntd.0006941