Development of the Liquid Chromatography Tandem Mass Spectrometry Method for Determination of Chloroquine and Desethylchloroquine in Human Plasma

Objective: Several studies reported a relationship between adverse effect and elevated blood concentration of chloroquine (CQ) and its active metabolite, desethylchloroquine (DCQ). Therefore, therapeutic drug monitoring of these drugs might be useful. This study aims to develop and validate a liqui...

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Bibliographic Details
Main Authors: Rasda Boonprasert, Jureeporn Sri-in, Piyapat Pongnarin, Somruedee Chatsiricharoenkul, Weerawadee Chandranipapongse
Format: Article
Language:English
Published: Mahidol University 2020-07-01
Series:Siriraj Medical Journal
Subjects:
Online Access:https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/244154