An emerging and variant viral promoter of HIV-1 subtype C exhibits low-level gene expression noise

An emerging and variant viral promoter of HIV-1 subtype C exhibits low-level gene expression noise

Abstract Background We observe the emergence of several promoter-variant viral strains in India during recent years. The variant viral promoters contain additional copies of transcription factor binding sites present in the viral modulatory region or enhancer, including RBEIII, LEF-1, Ap-1 and/or NF...

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Bibliographic Details
Main Authors: Haider Ali, Disha Bhange, Kavita Mehta, Yuvrajsinh Gohil, Harshit Kumar Prajapati, Siddappa N. Byrareddy, Shilpa Buch, Udaykumar Ranga
Format: Article
Language:English
Published: BMC 2021-09-01
Series:Retrovirology
Subjects:
HIV-1
Subtype C
Transcriptional silence
LTR
Latency reversal
Sequence duplication
Online Access:https://doi.org/10.1186/s12977-021-00572-2

Internet

https://doi.org/10.1186/s12977-021-00572-2

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