A Double-weighted Normalization Method for Identifying Differential Expression of RNA-seq Data

The normalization of high-throughput sequencing data from different sequencing conditions is a critical step of the entire high-throughput data analysis and processing. Normalization is important for the identification of gene structures and differentially expressed genes, which has great impact on...

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Bibliographic Details
Main Authors: Xiaohui Wu, Chuang Zhao, Yaru Su
Format: Article
Language:English
Published: Bulgarian Academy of Sciences 2014-12-01
Series:International Journal Bioautomation
Subjects:
Online Access:http://www.biomed.bas.bg/bioautomation/2014/vol_18.4/files/18.4_03.pdf