ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

ATAC-seq footprinting unravels kinetics of transcription factor binding during zygotic genome activation

Footprinting analysis allows genome-wide investigation of transcription factor (TF) binding on chromatin. Here the authors developed a framework termed TOBIAS aimed at identifying footprints of chromatin-associated proteins from ATAC-seq accessibility profiles and apply it to zygotic development dat...

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Bibliographic Details
Main Authors: Mette Bentsen, Philipp Goymann, Hendrik Schultheis, Kathrin Klee, Anastasiia Petrova, René Wiegandt, Annika Fust, Jens Preussner, Carsten Kuenne, Thomas Braun, Johnny Kim, Mario Looso
Format: Article
Language:English
Published: Nature Publishing Group 2020-08-01
Series:Nature Communications
Online Access:https://doi.org/10.1038/s41467-020-18035-1

Internet

https://doi.org/10.1038/s41467-020-18035-1

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