PGC1α Loss Promotes Lung Cancer Metastasis through Epithelial-Mesenchymal Transition

PGC1α Loss Promotes Lung Cancer Metastasis through Epithelial-Mesenchymal Transition

PGC1α oppositely regulates cancer metastasis in melanoma, breast, and pancreatic cancer; however, little is known about its impact on lung cancer metastasis. Transcriptome and in vivo xenograft analysis show that a decreased PGC1α correlates with the epithelial–mesenchymal transition (EMT) and lung...

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Bibliographic Details
Main Authors: Taek-In Oh, Mingyu Lee, Yoon-Mi Lee, Geon-Hee Kim, Daekee Lee, Jueng Soo You, Sun Ha Kim, Minyoung Choi, Hyonchol Jang, Yeong-Min Park, Hyun-Woo Shin, Dong Hoon Shin, Ji-Hong Lim
Format: Article
Language:English
Published: MDPI AG 2021-04-01
Series:Cancers
Subjects:
lung cancer
PGC1α
ID1
TCF4
TWIST1
EMT
Online Access:https://www.mdpi.com/2072-6694/13/8/1772

Internet

https://www.mdpi.com/2072-6694/13/8/1772

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