Functions of ubiquitin and SUMO in DNA replication and replication stress

Complete and faithful duplication of its entire genetic material is one of the essential prerequisites for a proliferating cell to maintain genome stability. Yet, during replication DNA is particularly vulnerable to insults. On the one hand, lesions in replicating DNA frequently cause a stalling of...

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Bibliographic Details
Main Authors: Néstor eGarcía-Rodríguez, Ronald P Wong, Helle D Ulrich
Format: Article
Language:English
Published: Frontiers Media S.A. 2016-05-01
Series:Frontiers in Genetics
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fgene.2016.00087/full