Biologic phenotyping of the human small airway epithelial response to cigarette smoking.

Biologic phenotyping of the human small airway epithelial response to cigarette smoking.

The first changes associated with smoking are in the small airway epithelium (SAE). Given that smoking alters SAE gene expression, but only a fraction of smokers develop chronic obstructive pulmonary disease (COPD), we hypothesized that assessment of SAE genome-wide gene expression would permit biol...

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Bibliographic Details
Main Authors: Ann E Tilley, Timothy P O'Connor, Neil R Hackett, Yael Strulovici-Barel, Jacqueline Salit, Nancy Amoroso, Xi Kathy Zhou, Tina Raman, Larsson Omberg, Andrew Clark, Jason Mezey, Ronald G Crystal
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3145669?pdf=render

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http://europepmc.org/articles/PMC3145669?pdf=render

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