LncRNA TUG1 promoted KIAA1199 expression via miR-600 to accelerate cell metastasis and epithelial-mesenchymal transition in colorectal cancer

LncRNA TUG1 promoted KIAA1199 expression via miR-600 to accelerate cell metastasis and epithelial-mesenchymal transition in colorectal cancer

Abstract Background LncRNA TUG1 has been reported to be highly expressed in CRC samples and cells and promoted metastasis by affecting EMT, indicating a poor prognosis for colorectal cancer (CRC). In this study, we determined the underlying mechanism for tumor oncogenesis of lncRNA TUG1 in CRC metas...

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Bibliographic Details
Main Authors: Junfeng Sun, Jiyi Hu, Guojun Wang, Zhen Yang, Chunlin Zhao, Xiefu Zhang, Jiaxiang Wang
Format: Article
Language:English
Published: BMC 2018-05-01
Series:Journal of Experimental & Clinical Cancer Research
Subjects:
lncRNA TUG1
KIAA1199
miR-600
Colorectal cancer
EMT
Metastasis
Online Access:http://link.springer.com/article/10.1186/s13046-018-0771-x

Internet

http://link.springer.com/article/10.1186/s13046-018-0771-x

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