An ES-like pluripotent state in FGF-dependent murine iPS cells.

Recent data demonstrates that stem cells can exist in two morphologically, molecularly and functionally distinct pluripotent states; a naïve LIF-dependent pluripotent state which is represented by murine embryonic stem cells (mESCs) and an FGF-dependent primed pluripotent state represented by murine...

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Main Authors: Bruno Di Stefano, Christa Buecker, Federica Ungaro, Alessandro Prigione, Hsu-Hsin Chen, Maaike Welling, Maureen Eijpe, Gustavo Mostoslavsky, Paul Tesar, James Adjaye, Niels Geijsen, Vania Broccoli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-12-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3012723?pdf=render