Senescence and tumor suppression [version 1; referees: 2 approved]

Cellular senescence has emerged as a potent tumor suppression mechanism that restrains proliferation of cells at risk for malignant transformation. Although senescent cells have permanently exited the cell cycle, their presence can have detrimental effects on the surrounding tissue, largely due to t...

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Bibliographic Details
Main Authors: Philip Hinds, Jodie Pietruska
Format: Article
Language:English
Published: F1000 Research Ltd 2017-12-01
Series:F1000Research
Subjects:
Online Access:https://f1000research.com/articles/6-2121/v1