Recombinant Heat Shock Protein 70 in Combination with Radiotherapy as a Source of Tumor Antigens to Improve Dendritic Cell Immunotherapy

Recombinant Heat Shock Protein 70 in Combination with Radiotherapy as a Source of Tumor Antigens to Improve Dendritic Cell Immunotherapy

Local radiotherapy (RT) plus intratumoral dendritic cell (DC) injection can mediate immunological response. We hypothesized that co-injection of exogenous recombinant heat shock protein 70 (rHsp70) in combination with RT-DC could be as effective as co-injection of HSP-peptide for evoking specific im...

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Bibliographic Details
Main Authors: Yu-Shan eWang, Shih-Jen eLiu, Su-Chen eHuang, Chao-Chun eChang, Yi-Chun eHuang, Weng-Lam eFong, Mau-Shin eChi, Kwan-Hwa eChi
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-10-01
Series:Frontiers in Oncology
Subjects:
Dendritic Cells
Immunotherapy
Radiotherapy
Tumor Microenvironment
heat shock protein 70
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00149/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fonc.2012.00149/full

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