The adaptor protein Grb2 is not essential for the establishment of the glomerular filtration barrier.

The kidney filtration barrier is formed by the combination of endothelial cells, basement membrane and epithelial cells called podocytes. These specialized actin-rich cells form long and dynamic protrusions, the foot processes, which surround glomerular capillaries and are connected by specialized i...

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Bibliographic Details
Main Authors: Nicolas Bisson, Julie Ruston, Marie Jeansson, Rachel Vanderlaan, W Rod Hardy, Jianmei Du, Samer M Hussein, Richard J Coward, Susan E Quaggin, Tony Pawson
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3511449?pdf=render