Activation of the Ubiquitin Proteasome Pathway by Silk Fibroin Modified Chitosan Nanoparticles in Hepatic Cancer Cells

Activation of the Ubiquitin Proteasome Pathway by Silk Fibroin Modified Chitosan Nanoparticles in Hepatic Cancer Cells

Silk fibroin (SF) is a protein with bulky hydrophobic domains and can be easily purified as sericin-free silk-based biomaterial. Silk fibroin modified chitosan nanoparticle (SF-CSNP), a biocompatible material, has been widely used as a potential drug delivery system. Our current investigation studie...

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Bibliographic Details
Main Authors: Ming-Hui Yang, Tze-Wen Chung, Yi-Shan Lu, Yi-Ling Chen, Wan-Chi Tsai, Shiang-Bin Jong, Shyng-Shiou Yuan, Pao-Chi Liao, Po-Chiao Lin, Yu-Chang Tyan
Format: Article
Language:English
Published: MDPI AG 2015-01-01
Series:International Journal of Molecular Sciences
Subjects:
silk fibroin
chitosan nanoparticle
biomaterial
proteomics
ubiquitin proteasome pathway
Online Access:http://www.mdpi.com/1422-0067/16/1/1657

Internet

http://www.mdpi.com/1422-0067/16/1/1657

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