Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction.

Mutation in MRPS34 compromises protein synthesis and causes mitochondrial dysfunction.

The evolutionary divergence of mitochondrial ribosomes from their bacterial and cytoplasmic ancestors has resulted in reduced RNA content and the acquisition of mitochondria-specific proteins. The mitochondrial ribosomal protein of the small subunit 34 (MRPS34) is a mitochondria-specific ribosomal p...

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Bibliographic Details
Main Authors: Tara R Richman, Judith A Ermer, Stefan M K Davies, Kara L Perks, Helena M Viola, Anne-Marie J Shearwood, Livia C Hool, Oliver Rackham, Aleksandra Filipovska
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-03-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC4376678?pdf=render

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http://europepmc.org/articles/PMC4376678?pdf=render

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