A polymorphism (rs2295080) in mTOR promoter region and its association with gastric cancer in a Chinese population.

BACKGROUND: As an imperative part of PI3K/Akt/mTOR pathway, mammalian target of rapamycin (mTOR) has been demonstrated to increase in gastric cancer cells and tumors. Our research explored the relationship between single nucleotide polymorphism (SNP) rs2295080 in mTOR promoter region and the risk of...

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Bibliographic Details
Main Authors: Ming Xu, Guoquan Tao, Meiyun Kang, Yan Gao, Haixia Zhu, Weida Gong, Meilin Wang, Dongmei Wu, Zhengdong Zhang, Qinghong Zhao
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3612103?pdf=render