Evolution and expansion of the <it>Mycobacterium tuberculosis </it>PE and PPE multigene families and their association with the duplication of the ESAT-6 (<it>esx</it>) gene cluster regions

<p>Abstract</p> <p>Background</p> <p>The PE and PPE multigene families of <it>Mycobacterium tuberculosis </it>comprise about 10% of the coding potential of the genome. The function of the proteins encoded by these large gene families remains unknown, althoug...

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Bibliographic Details
Main Authors: Warren Robin M, van Helden Paul D, Lee Hyeyoung, Kim Yeun, Sampson Samantha L, Gey van Pittius Nicolaas C
Format: Article
Language:English
Published: BMC 2006-11-01
Series:BMC Evolutionary Biology
Online Access:http://www.biomedcentral.com/1471-2148/6/95