Lmx1a encodes a rostral set of mesodiencephalic dopaminergic neurons marked by the Wnt/B-catenin signaling activator R-spondin 2.

Recent developments in molecular programming of mesodiencephalic dopaminergic (mdDA) neurons have led to the identification of many transcription factors playing a role in mdDA specification. LIM homeodomain transcription factor Lmx1a is essential for chick mdDA development, and for the efficient di...

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Main Authors: Elisa J Hoekstra, Lars von Oerthel, Lars P van der Heide, Willemieke M Kouwenhoven, Jesse V Veenvliet, Iris Wever, Yong-Ri Jin, Jeong K Yoon, Annemarie J A van der Linden, Frank C P Holstege, Marian J Groot Koerkamp, Marten P Smidt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3774790?pdf=render