A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis.

A systems biology approach reveals the role of a novel methyltransferase in response to chemical stress and lipid homeostasis.

Using small molecule probes to understand gene function is an attractive approach that allows functional characterization of genes that are dispensable in standard laboratory conditions and provides insight into the mode of action of these compounds. Using chemogenomic assays we previously identifie...

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Bibliographic Details
Main Authors: Elena Lissina, Brian Young, Malene L Urbanus, Xue Li Guan, Jonathan Lowenson, Shawn Hoon, Anastasia Baryshnikova, Isabelle Riezman, Magali Michaut, Howard Riezman, Leah E Cowen, Markus R Wenk, Steven G Clarke, Guri Giaever, Corey Nislow
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-10-01
Series:PLoS Genetics
Online Access:http://europepmc.org/articles/PMC3197675?pdf=render

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http://europepmc.org/articles/PMC3197675?pdf=render

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