Establishment of a zebrafish hematological disease model induced by 1,4-benzoquinone

Establishment of a zebrafish hematological disease model induced by 1,4-benzoquinone

Benzene exposure is associated with various hematological disorders, in particular leukemia. The reactive metabolite of benzene, 1,4-benzoquinone (BQ), generated in bone marrow, is suggested to be a key molecule in mediating benzene-induced hematotoxicity and carcinogenicity. However, its pathogenic...

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Bibliographic Details
Main Authors: Ao Zhang, Mei Wu, Junliang Tan, Ning Yu, Mengchang Xu, Xutong Yu, Wei Liu, Yiyue Zhang
Format: Article
Language:English
Published: The Company of Biologists 2019-03-01
Series:Disease Models & Mechanisms
Subjects:
1,4-Benzoquinone
Hematotoxicity
Neutrophilia
c-myb
Zebrafish
Online Access:http://dmm.biologists.org/content/12/3/dmm037903

Internet

http://dmm.biologists.org/content/12/3/dmm037903

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