Human Second Window Pre-Conditioning and Post-Conditioning by Nitrite Is Influenced by a Common Polymorphism in Mitochondrial Aldehyde Dehydrogenase

Summary: Pre-conditioning is an exciting physiological phenomenon that, despite great efforts, has so far resisted translation to mainstream clinical medicine. Many potential triggers (e.g., ischemia of the organ in question or a remote organ, many different drugs) have been investigated, but recent...

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Main Authors: Julian O.M. Ormerod, MD, PhD, Jonathan D.W. Evans, MD, Hussain Contractor, MD, PhD, Matteo Beretta, PhD, Sayqa Arif, MD, PhD, Bernadette O. Fernandez, PhD, Martin Feelisch, PhD, Bernd Mayer, PhD, Rajesh K. Kharbanda, MD, PhD, Michael P. Frenneaux, MD, Houman Ashrafian, MD, PhD
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:JACC: Basic to Translational Science
Online Access:http://www.sciencedirect.com/science/article/pii/S2452302X16301723