Microarray profiling reveals the integrated stress response is activated by halofuginone in mammary epithelial cells

<p>Abstract</p> <p>Background</p> <p>The small molecule Halofuginone (HF) is a potent regulator of extracellular matrix (ECM ) gene expression and is unique in its therapeutic potential. While the basis for HF effects is unknown, inhibition of TGFβ signaling and activat...

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Bibliographic Details
Main Authors: Kuo Winston P, Kim Jihoon, Mazitschek Ralph, Kamberov Yana G, Whitman Malcolm
Format: Article
Language:English
Published: BMC 2011-10-01
Series:BMC Research Notes
Online Access:http://www.biomedcentral.com/1756-0500/4/381