Non-catalytic motor domains enable processive movement and functional diversification of the kinesin-14 Kar3

Motor proteins of the conserved kinesin-14 family have important roles in mitotic spindle organization and chromosome segregation. Previous studies have indicated that kinesin-14 motors are non-processive enzymes, working in the context of multi-motor ensembles that collectively organize microtubule...

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Bibliographic Details
Main Authors: Christine Mieck, Maxim I Molodtsov, Katarzyna Drzewicka, Babet van der Vaart, Gabriele Litos, Gerald Schmauss, Alipasha Vaziri, Stefan Westermann
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2015-01-01
Series:eLife
Subjects:
Online Access:https://elifesciences.org/articles/04489