Differential Effects of Sertraline in a Predator Exposure Animal Model of Post-Traumatic Stress Disorder

Differential Effects of Sertraline in a Predator Exposure Animal Model of Post-Traumatic Stress Disorder

Serotonin (5-HT), norepinephrine (NE), and other neurotransmitters are modulated in post-traumatic stress disorder (PTSD). In addition, pro-inflammatory cytokines (PIC) are elevated during the progression of the disorder. Currently, the only approved pharmacologic treatments for PTSD are the selec...

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Bibliographic Details
Main Authors: C. Brad eWilson, Leslie D. McLaughlin, Philip J. Ebenezer, Anand R. Nair, Rahul eDange, Joseph G. Harre, Thomas L. Shaak, David M Diamond, Joseph eFrancis
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-07-01
Series:Frontiers in Behavioral Neuroscience
Subjects:
Inflammation Mediators
Norepinephrine
Serotonin
Sertraline
elevated plus maze
SSRI
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00256/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnbeh.2014.00256/full

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