Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease.

Lp-PLA2, scavenger receptor class B type I gene (SCARB1) rs10846744 variant, and cardiovascular disease.

BACKGROUND:We previously reported association of SCARB1 SNP rs10846744 with common carotid IMT (cIMT) and cardiovascular disease (CVD) events. Since rs10846744 has been reported in association with Lp-PLA2 mass and activity, we hypothesized that inflammatory pathways might mediate the association of...

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Bibliographic Details
Main Authors: Ani Manichaikul, Xin-Qun Wang, Li Li, Jeanette Erdmann, Guillaume Lettre, Joshua C Bis, Dawn Waterworth, Mary Cushman, Nancy S Jenny, Wendy S Post, Walter Palmas, Michael Y Tsai, Lars Wallentin, Harvey White, Heribert Schunkert, Christopher J O'Donnell, David M Herrington, Stephen S Rich, Michelle L O'Donoghue, Annabelle Rodriguez
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6173398?pdf=render

Internet

http://europepmc.org/articles/PMC6173398?pdf=render

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