Alendronate/cRGD-Decorated Ultrafine Hyaluronate Dot Targeting Bone Metastasis

Alendronate/cRGD-Decorated Ultrafine Hyaluronate Dot Targeting Bone Metastasis

In this study, we report the hyaluronate dot (dHA) with multiligand targeting ability and a photosensitizing antitumor model drug for treating metastatic bone tumors. Here, the dHA was chemically conjugated with alendronate (ALN, as a specific ligand to bone), cyclic arginine-glycine-aspartic acid (...

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Bibliographic Details
Main Authors: Eunsol Lee, Jaeduk Park, Yu Seok Youn, Kyung Taek Oh, Dongin Kim, Eun Seong Lee
Format: Article
Language:English
Published: MDPI AG 2020-11-01
Series:Biomedicines
Subjects:
hyaluronate dot
alendronate
cyclic RGD
bone metastasis
photodynamic tumor therpy
Online Access:https://www.mdpi.com/2227-9059/8/11/492

Internet

https://www.mdpi.com/2227-9059/8/11/492

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